Colin J. Barnstable


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Dr. Colin Barnstable received a B.A. (1st class honors) in biochemistry from University College, Oxford, and M.A.  and D.Phil degrees in genetics from Wolfson College, Oxford.   As a student in the laboratory of Sir Walter Bodmer he carried out studies of the genetics and molecular structure of HLA antigens, including producing a seminal paper on the production of monoclonal antibodies against a number of human molecules including HLA-A,B,C antigens.

 

Dr. Barnstable moved to the laboratory of Dr. Torsten N. Wiesel in the Department of Neurobiology , Harvard Medical School as a Damon Runyon-Walter Winchell Cancer fund fellow.  It was here that he began his studies of the mammalian retina, developing a series of monoclonal antibodies that allowed the identification of specific retinal cell types.

 

He then continued his work as a faculty member of Harvard Medical School for a further three years. Dr. Barnstable then spent five years on the faculty of the Rockefeller University in New York before moving to Yale School of Medicine as Research director of the Yale Eye Center.  In 2006 Dr. Barnstable became Professor and founding Chair of the Department of Neural and Behavioral Sciences at Penn State College of Medicine in Hershey, PA.

 

Dr. Barnstable’s work has covered many aspects of the molecular regulation of retinal development as well as structural aspects of visual cortex and changes during a number of neurodegenerative conditions.  His recent work has focused on the role of the epigenome in regulating retinal development and degeneration and on the molecular mechanisms regulating oxidative stress in a number of degenerative diseases.

 

Dr. Barnstable also recognizes the importance of translating basic research in to commercial practice and has served as Vice president R&D for Molecular Circuitry, Inc, and is a co-founder of Skyran Biologics, Inc.

 

Dr. Barnstable’s work has appeared in over 190 publications and has been cited over 14,000 times by over 11,000 other publications.  He has also served as co-editor of a series of books on Ophthalmology published by the Humana Press imprint of Springer.  He has served on the editorial boards of multiple journals including the Journal of Neuroscience, Journal of Neurochemistry, Journal of Ocular Biology, Diseases and Informatics, and Experimental Eye Research.  He currently serves on the editorial boards of Molecular Neurobiology, Journal of Molecular Neuroscience and Neural Regeneration Research.

 

Dr. Barnstable has served as a member and chair of numerous NIH study sections and on the scientific advisory boards of the Foundation Fighting Blindness (Canada) and the Macula Vision Research Foundation.  He has received a number of awards including a Sloan Foundation fellowship, a Drs. C. and F. Demuth Swiss Medical Foundation International Award in Neuroscience, a Jules and Doris Stein Research to Prevent Blindness Professorship, a Senior Scientific Investigator, Research to Prevent Blindness, Inc., ARVO Fellowship, and  a Melvin Jones Fellowship,from Lions International. 

 

As a consultant with CRDF global, Dr. Barnstable has helped teach professional development courses in a number of Asian, Central Asian and Middle Eastern countries.  His extensive collaborations in China have resulted in visiting professorships awarded byXi’an Medical University, the Henan Eye Institute, the Eye Hospital of Wenzhou Medical University and He University.